Australian Primary Care professionals who completed an online survey showed existing knowledge of the risk factors for dementia and were able to identify some hurdles that may need to be overcome to more successfully implement dementia risk reduction in Primary Care. This work is now published in the Australian Journal Read more…
The 2019 publication of the SPRINT-MIND* study has once again raised the possibility that sufficient control of systolic blood pressure (BP) may reduce risk of developing cognitive impairment1. SPRINT MIND was a randomised open label two arm trial with one arm aiming to achieve systolic BPs of <120mmHg and the Read more…
New research has come out showing that a group of nonsteroidal anti-inflammatory drugs (NSAID) may have therapeutic effects for Alzheimer’s Disease. Dr Jack Rivers-Auty and his team have been investigating the impact of nonsteroidal anti-inflammatory drugs (NSAIDs) in reducing neuroinflammation. Using mice models Jack and his team have found that the Read more…
In epidemiological research of risk factors for dementia, education is firmly established as a protective mechanism. PhD candidate Janet Maccora from UNSW summarises some recent papers from economists that demonstrate that while education may well be protective, cost and context should be important considerations when thinking about prevention. A recent Read more…
A team from Imperial College London puts forward an argument for the use of clinical trial simulators in planning future trials in Alzheimer’s disease The growing global burden of dementia reflects an aging population, where Alzheimer’s disease (AD) is the most common cause of dementia accounting for roughly two Read more…
Continuing our series of science commentaries Barbora Silarova and Rachel Collins from the Universities of Exeter, UK and UNSW, Australia, consider whether lessons can be learned from other non-communicable diseases… Dementia represents one of the biggest challenges for health and social care this century [1]. Since the development of Read more…
In the second of our series of science commentaries Dr Ruth Peters discusses the methodology, directions and findings used in two recent reviews on dementia prevention. Two recent reviews have approached the question of dementia prevention using very different methodologies and from different directions. The Lancet Commission, ‘dementia prevention, intervention Read more…
In the first of a series of science commentaries from leading experts in the field of dementia research, Emeritus Professor A David Smith argues that the typical observational study approach in dementia prevention to identify modifiable risk factors should include consideration of subgroups, and interactions between risk factors, to ensure Read more…