Evidence hub – evidence synthesis
The evidence synthesis group brings together researchers and academics to collaborate, share expertise and generate high quality systematic reviews and meta-analyses relating to dementia, its prevention or delay.
IRNDP Evidence Synthesis Work
Our systematic reviews and meta-analyses relate to multiple risk factors for incident dementia, potential interventions and methodologies used for cognitive assessment.
We are keen to ensure that our work translates into clinical practice where possible and always raises new questions, highlights gaps in the evidence base and signposts the key directions for future research.
Examples of our work:
Clifford, A, Lang, L, Chen, R et al 2016, 'Exposure to air pollution and cognitive functioning across the life course - A systematic literature review', Environmental Research, vol. 147, pp. 383-398.
Peters, R., Ee, N., Peters, J., Booth, A., Mudway, I., & Anstey, K. J. (2019). Air Pollution and Dementia: A Systematic Review. Journal of Alzheimer's Disease, (Preprint), 1-19.
Peters R, Peters J, Warner J, Beckett N, Bulpitt C. Alcohol, dementia and cognitive decline in the elderly: a systematic review. Age Ageing 2008; 37: 505-512
Pedditzi E, Peters R, Beckett N. The risk of overweight/obesity in midlife and late life for the development of dementia: systematic review and meta-analysis of longitudinal studies. Age Ageing 2016; 45(1):14-21
Danat, I. M., Clifford, A., Partridge, M., Zhou, W., Bakre, A. T., Chen, A., ... & Anstey, K. J. (2019). Impacts of Overweight and Obesity in Older Age on the Risk of Dementia: A Systematic Literature Review and a Meta-Analysis. Journal of Alzheimer's Disease, (Preprint), 1-13.
Anstey, K. J., Ashby-Mitchell, K., & Peters, R. (2017). Updating the evidence on the association between serum cholesterol and risk of late-life dementia: review and meta-analysis. Journal of Alzheimer's Disease, 56(1), 215-228. https://www.ncbi.nlm.nih.gov/pubmed/27911314
Peters R, Schuchman M, Peters J, Carlson MC, Yasar S.Relationship Between Antihypertensive Medications and Cognitive Impairment: Part II. Review of Physiology and Animal Studies. Curr Hypertens Rep. 2016 Aug;18(8):66. doi: 10.1007/s11906-016-0673-2.
Peters R, Booth A, Peters J. A systematic review of Calcium Channel Blocker use and cognitive decline/dementia in the elderly Journal of Hypertension 2014 32(10) 1945-1958 https://www.ncbi.nlm.nih.gov/pubmed/25068540
Peters R, Poulter R, Warner J, Beckett N, Burch, L, Bulpitt C. Smoking, dementia and cognitive decline in the elderly, a systematic review, BMC Geriatrics 2008 8;36 DOI 10.1186/1471-2318-8-36.
We combine our expertise in different ways carrying our reviews and analyses centrally or separately for each study. We very much welcome new members. If you are interested in joining please contact us.
Terms and conditions
The recommendations, views or findings expressed in studies, trials or articles are expressly those of the authors. Such recommendations, views or findings do not represent the recommendations, views or findings of the International Research Network on Dementia Prevention (IRNDP), its Leadership Committee or Independent Advisory Group or any collaborating institutions. IRNDP accepts no responsibility for the accuracy or content, or liability in respect of studies submitted to it.